Six-Month Outcomes From a Randomized Controlled Trial to Prevent Perinatal Depression in Low-Income Home Visiting Clients




S. Darius Tandon, Julie A. Leis, Tamar Mendelson, Deborah F. Perry, and Karen Kemp

Type of Product

Journal Publication

Program Models Included

  • Other Models


Perinatal depression (PD) has negative consequences for mothers and children and is more prevalent among women of low socioeconomic status. Home visitation programs serve low-income pregnant women at risk for PD. This study tested the efficacy of a group-based cognitive behavioral intervention (Mothers and Babies Course; MB) in reducing depressive symptoms and preventing the onset of perinatal depression among low-income women enrolled in home visitation. A randomized controlled trial was conducted. Seventy-eight women who were pregnant or had a child less than 6 months of age and who were assessed as at risk for PD were randomized to the MB intervention or usual home visiting services. Depressive symptoms were assessed at baseline and 1-week, 3- and 6-months post-intervention; depressive episodes were assessed with a clinical interview at the 6-month follow-up. Depressive symptoms declined at a significantly greater rate for intervention participants than usual care participants between baseline and 1-week, 3 and 6 months post-intervention. At the 6-month follow-up, 15 % of women who received the MB intervention had experienced a major depressive episode as compared with 32 % of women receiving usual care. Integrating mental health interventions into home visitation appears to be a promising approach for preventing PD. Cognitive behavioral techniques can be effective in preventing depression in perinatal populations and treating it. (author abstract)

Data Collection Methods

  • Standardized assessment tools



For More Information

Tandon, S. D., Leis, J. A., Mendelson, T., Perry, D. F., & Kemp, K. (2014). Six-month outcomes from a randomized controlled trial to prevent perinatal depression in low-income home visiting clients. Maternal and Child Health Journal, 18(4),  873–881. https://doi.org/10.1007/s10995-013-1313-y
Author Contact Information:
S. Darius Tandon


  • Participant, Family, and Program Outcomes
  • Program Enhancements, Innovations, and Promising Approaches